Dogs are behind cats, and the honest timeline is long.
There is no FDA-approved GLP-1 for dogs, and no canine GLP-1 trial has been announced. Dogs are named as the next species by the companies testing in cats, but no canine study has started. What is at the FDA for dogs is not a GLP-1 and not a weight-loss drug, and the one canine weight-loss drug ever approved was pulled from the market.
The canine programmes
Neither of these is a GLP-1. They are tracked because they are the regulatory and historical context readers most often mistake for one.
| Programme | Species | Expected readout | Status | Detail |
|---|---|---|---|---|
| Not GLP-1sTracked as regulatory and historical context | ||||
| LOY-002LoyalNot a GLP-1 | Dogs | Company-projected launch before end of 2026Estimated, not company-confirmed | Two of three FDA technical sections accepted: reasonable expectation of effectiveness in February 2025 and target animal safety in January 2026. The manufacturing section remains outstanding. | Full statusFull status for LOY-002 |
| Slentrol (dirlotapide)Pfizer Animal HealthNot a GLP-1 | Dogs | Not applicable | The first and so far only FDA-approved canine weight-loss drug. Approved 2007, voluntarily discontinued in 2013. | Full statusFull status for Slentrol (dirlotapide) |
Nothing in this table is FDA-approved for weight loss in cats or dogs. A programme being in a pivotal study is not an approval, and an expected readout is not a result. Dates marked “estimated” come from reporting or analysis, not from the sponsor. Last verified 2026-07-31.
Read next
- Ozempic for dogsThe real status, and why vets cannot prescribe it.
- Dog obesityThe condition, and what actually works today.
- Is my dog overweight?Check with the 9-point veterinary scale.
- Labrador weight lossThe breed with a documented genetic appetite variant.
- Weight-loss dog foodWhat is available now, compared.
- Dog body condition tool60-second canine BCS assessment.
Nothing here is veterinary advice. Human GLP-1 medications cannot legally be prescribed for pets and are not safe to give them. Talk to your vet.